Native to the Americas, ranging from the Southwestern United States through Mexico to South America, Sun Opener is a shrub with a deep history in Aztec and Highland Mexican herbalism. It is famously known as "Sinicuichi." Legend suggests the plant was used to help "open" the memory of past events or to hear the "voices of the sun," leading to its poetic common name.

Key actions include serving as an auditory hallucinogen (in traditional fermented preparations), sedative, and muscle relaxant. It also acts as a vasodilator and a mild diuretic, often used to promote a sense of deep tranquility.

The primary active alkaloids are quinolizidine derivatives, most notably cryogenine (vertine), which is responsible for its sedative and relaxing effects. It also contains nesodine and lythrine.

The leaves are the primary part used. Traditionally, they are slightly wilted and then crushed or steeped to extract the active compounds.

Use with care. Some users report a "golden tint" to their vision or altered hearing (auditory distortions) which can be disorienting. High doses may lead to muscle soreness or fatigue the following day. Not recommended for those with pre-existing heart conditions or for use during pregnancy.

Historically used to treat inflammatory conditions, syphilis, and to help with wound healing. It was traditionally prepared as a "sun tea"—the leaves were crushed, mixed with water, and left in the sun to ferment for 24 hours before consumption to activate its unique properties.